Ultra-high-density mapping during ventricular tachycardia ablation reduced the risk of recurrence or disease-related death compared to conventional point-by-point mapping (HR 0.623).
Cohort (n=122)
No
Does ultra-high-density mapping reduce recurrence or disease-related death in patients undergoing catheter ablation of ventricular tachycardia?
Ultra-high-density mapping during VT ablation is associated with improved long-term outcomes compared to conventional point-by-point mapping.
Effect estimate: HR 0.623 (95% CI 0.390-0.995)
Absolute Event Rate: 52.4% vs 69.6%
p-value: p=0.048
Ultra-high-density (UHD) mapping can improve scar area detection and fast activation mapping in patients undergoing catheter ablation of ventricular tachycardia (VT). The aim of the present study was to compare the outcome after VT ablation guided by UHD and conventional point-by-point 3D-mapping. The acute and long-term ablation outcome of 61 consecutive patients with UHD mapping (64-electrode mini-basket catheter) was compared to 61 consecutive patients with conventional point-by-point 3D-mapping using a 3.5 mm tip catheter. Patients, whose ablation was guided by UHD mapping had an improved 24-months outcome in comparison to patients with conventional mapping (cumulative incidence estimate of the combination of recurrence or disease-related death of 52.4% (95% confidence interval (CI) 36.9-65.7; recurrence: n = 25; disease-related death: n = 4) versus 69.6% (95% CI 55.9-79.8); recurrence: n = 31; disease-related death n = 11). In a cause-specific Cox proportional hazards model, UHD mapping (hazard ratio (HR) 0.623; 95% CI 0.390-0.995; P = 0.048) and left ventricular ejection fraction > 30% (HR 0.485; 95% CI 0.290-0.813; P = 0.006) were independently associated with lower rates of recurrence or disease-related death. Other procedural parameters were similar in both groups. In conclusion, UHD mapping during VT ablation was associated with fewer VT recurrences or disease-related deaths during long-term follow-up in comparison to conventional point-by-point mapping. Complication rates and other procedural parameters were similar in both groups.
Schleberger et al. (Wed,) conducted a cohort in Scar-related ventricular tachycardia (n=122). Ultra-high-density (UHD) mapping vs. Conventional point-by-point 3D-mapping was evaluated on Recurrence or disease-related death at 24 months (HR 0.623, 95% CI 0.390-0.995, p=0.048). Ultra-high-density mapping during ventricular tachycardia ablation reduced the risk of recurrence or disease-related death compared to conventional point-by-point mapping (HR 0.623).