Key result
16-week HIIT and Mediterranean diet substantially improve physical quality of life versus control post-MI.
Why the study?
To determine the impact of low- versus high-volume HIIT programs with Mediterranean diet recommendations on HRQoL and lifestyle modification after MI, and examine relationships with anxiety and depression.
Does supervised high-intensity interval training combined with Mediterranean diet recommendations improve health-related quality of life and lifestyle modification in post-myocardial infarction patients?
RCT (n=80)
Single-blind (cardiology and nurse staff blinded to randomization)
Stratified randomization by etiology and age
Yes
Does supervised high-intensity interval training combined with Mediterranean diet recommendations improve health-related quality of life and lifestyle modification in post-myocardial infarction patients?
A 16-week supervised high-intensity interval training program combined with Mediterranean diet recommendations significantly improves quality of life, mental health, and lifestyle habits in post-myocardial infarction patients.
Supports adding supervised HIIT plus Mediterranean diet to post-MI rehabilitation; extends RCT evidence for combined lifestyle interventions on physical HRQoL.
This study aims to determine the impact of 2 (low vs high volume) high-intensity interval training (HIIT) programs with Mediterranean diet (MedDiet) recommendations on health-related quality of life (HRQoL) and lifestyle modification, and to examine the relationships between the changes in anxiety and depression with HRQoL and lifestyle variables after myocardial infarction (MI). Participants (n = 80) were randomized to attention control or one of the two supervised HIIT groups (2 d/weeks). Surveys before and after intervention (16 weeks): HRQoL (SF-36), anxiety and depression (HADS), MedDiet adherence (MEDAS), and physical activity (PA) and sedentary behavior (SB) levels. After intervention, there were improvements ( P < .05) in HRQoL, HADS scores, and MedDiet adherence, with higher PA level in both HIIT groups with no between-HIIT group differences. The HADS score decline correlated ( P < .05) with both the increase in physical component of SF-36 ( r = .42), the overall metabolic expenditure ( r = .26), and adherence to the MedDiet ( r = .24), and the reduction in the SB ( r = .35). HIIT exercise intervention with MedDiet recommendations improved HRQoL, along with reduced anxiety and depression symptoms, and a healthier lifestyle after MI. Better mental health was related to higher values of PA and MedDiet adherence.
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Jayo-Montoya et al. (2022) conducted an RCT in Post-Myocardial Infarction (n=80). Aerobic High-Intensity Interval Training (HIIT) and Mediterranean Diet Recommendations vs. Attention control was evaluated on Change in Physical Component Summary (SF-36) (Hedges' g 1.29, p=<0.001). A 16-week aerobic high-intensity interval training program with Mediterranean diet recommendations significantly improved the physical component of health-related quality of life (Hedges' g 1.29) compared to attention control in post-myocardial infarction patients.
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