Value of immediate coronary angioplasty following intracoronary thrombolysis in acute myocardial infarction
Why the study?
Does immediate coronary angioplasty following intracoronary thrombolysis improve global ejection fraction and clinical outcomes in patients with acute myocardial infarction?
Population
533 patients with acute myocardial infarction of less than 4-h duration
Comparison
Immediate coronary angioplasty following… vs Conventional treatment or intracoronary…
Design
RCT, Randomized trial
Follow-up
median 24 months
Authors
Discussion
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Member takes
Implication
Supports adjunctive angioplasty after thrombolysis to improve LV recovery in AMI; extends randomized evidence for combined reperfusion strategies.
Structured PICO
Does immediate coronary angioplasty following intracoronary thrombolysis improve global ejection fraction and clinical outcomes in patients with acute myocardial infarction?
P
Population
533 patients with acute myocardial infarction of less than 4-h duration
I
Intervention
Immediate coronary angioplasty following intracoronary thrombolysis
C
Comparator
Conventional treatment or intracoronary thrombolysis without angioplasty
O
Outcome
Global ejection fractionsurrogate
Immediate coronary angioplasty following intracoronary thrombolysis in acute myocardial infarction improves global ejection fraction and long-term clinical outcomes compared to thrombolysis alone or conventional therapy.
Cite This Study
Suryapranata et al. (1987) studied this question.