Key result
Angioplasty following thrombolysis for acute myocardial infarction resulted in a higher reperfusion success rate than thrombolysis alone (91.4% vs 74.8%, p<0.01).
Why the study?
Does angioplasty following conventional thrombolysis improve reperfusion success and long-term prognosis compared to thrombolysis or angioplasty alone in patients with acute myocardial infarction?
Population
409 patients with acute myocardial infarction admitted to the hospital within 12 hours of symptom onset
Comparison
Angioplasty following conventional thrombolysis vs Thrombolysis alone or angioplasty alone
Design
Cohort
Follow-up
1 year
Authors
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May support post-thrombolysis angioplasty for AMI reperfusion; leaves open effects on prognosis versus primary angioplasty alone.
Cohort (n=409)
Does angioplasty following conventional thrombolysis improve reperfusion success and long-term prognosis compared to thrombolysis or angioplasty alone in patients with acute myocardial infarction?
Absolute Event Rate: 91.4% vs 74.8%
p-value: p=<0.01
Thrombolytic therapy with subsequent angioplasty is an effective strategy for achieving cardiac reperfusion and improving outcomes following acute myocardial infarction.
Hayashi et al. (2004) conducted a cohort in Acute Myocardial Infarction (n=409). Angioplasty after thrombolysis vs. Thrombolysis alone was evaluated on Reperfusion success rate (p=<0.01). Angioplasty following thrombolysis for acute myocardial infarction resulted in a higher reperfusion success rate than thrombolysis alone (91.4% vs 74.8%, p<0.01).
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