Key result
An estimated 67,900 Japanese encephalitis cases occur annually worldwide (incidence of 1.8 per 100,000), with approximately 75% of cases affecting children aged 0-14 years.
Systematic Review
Yes
The global incidence of Japanese encephalitis remains substantial at approximately 67,900 cases annually, highlighting the need for continued and expanded vaccination efforts.
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Sustained high pediatric incidence supports prioritized vaccination in endemic regions; extends prior global burden estimates with updated synthesis.
Campbell et al. (2011) conducted a systematic review in Japanese encephalitis. An estimated 67,900 Japanese encephalitis cases occur annually worldwide (incidence of 1.8 per 100,000), with approximately 75% of cases affecting children aged 0-14 years.
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