Key result
Wearable cardioverter-defibrillators can serve as a bridging therapy to prevent sudden cardiac death in patients with a low left ventricular ejection fraction during the first 40 to 90 days after a myocardial infarction.
Why the study?
Despite the risk of sudden cardiac death after myocardial infarction, implantable cardioverter-defibrillators are contraindicated early on, and wearable cardioverter-defibrillators lack sufficient recognition among interventional cardiologists.
Does the use of wearable cardioverter-defibrillators reduce sudden cardiac death in patients following myocardial infarction with reduced LVEF?
Does the use of wearable cardioverter-defibrillators reduce sudden cardiac death in patients following myocardial infarction with reduced LVEF?
Wearable cardioverter-defibrillators serve as a safe and potentially effective bridge to ICD implantation for preventing sudden cardiac death in the early phase after myocardial infarction with reduced LVEF, though patient compliance remains a critical challenge.
Answers are grounded in this paper and cite their sources.
May support wearable cardioverter-defibrillators as bridge in early post-MI low LVEF; leaves open randomized confirmation.
Sudden cardiac death is one of the leading causes of death in the older population. Compared with the general population, patients who experienced a myocardial infarction are four to six times more likely to experience sudden cardiac death. Though primary percutaneous coronary intervention considerably reduces mortality in patients who experienced a myocardial infarction, a non-negligible number of sudden cardiac deaths still occurs. Despite the high incidence rate of sudden cardiac deaths during the first month after myocardial infarction, prophylactic use of implantable cardioverter-defibrillators has so far failed to convey a survival benefit. Therefore, current clinical guidelines recommend that cardioverter-defibrillator implantation is contraindicated until 90 days after myocardial infarction. Wearable cardioverter-defibrillators were first approved for clinical use in 2002 and are currently considered as a bridge to therapy in patients with myocardial infarction with a reduced left ventricular ejection fraction in whom cardioverter-defibrillator implantation is temporarily not indicated. However, there is insufficient recognition among interventional cardiologists of the use of wearable cardioverter-defibrillators for preventing sudden cardiac death after myocardial infarction. Hence, we reviewed the evidence of the efficacy of wearable cardioverter-defibrillators used in patients following myocardial infarction to achieve better management of sudden cardiac death.
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Hioki et al. (2021) conducted a review in Myocardial infarction with reduced left ventricular ejection fraction. Wearable cardioverter-defibrillator (WCD) vs. Conventional medical therapy / No WCD was evaluated. Wearable cardioverter-defibrillators can serve as a bridging therapy to prevent sudden cardiac death in patients with a low left ventricular ejection fraction during the first 40 to 90 days after a myocardial infarction.
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