Key result
Heart failure independently increases the risk of stroke regardless of atrial fibrillation, and non-vitamin K antagonist oral anticoagulants represent a potential therapeutic option for stroke prevention.
Heart failure is an independent risk factor for stroke, and the CHA2DS2-VASc score may help identify high-risk patients who could benefit from targeted stroke prevention strategies even without atrial fibrillation.
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Does not yet support routine anticoagulation in HF without AF; leaves open need for RCTs of NOACs in this population.
Kim et al. (2018) conducted a review in Heart failure. Non-vitamin K antagonist oral anticoagulants (NOACs) vs. Warfarin was evaluated. Heart failure independently increases the risk of stroke regardless of atrial fibrillation, and non-vitamin K antagonist oral anticoagulants represent a potential therapeutic option for stroke prevention.
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