Why the study?
Do esmolol, sodium nitroprusside, and isoflurane differ in their ability to alter peripheral sympathetic responses to hypotension in anesthetized dogs?
Do esmolol, sodium nitroprusside, and isoflurane differ in their ability to alter peripheral sympathetic responses to hypotension in anesthetized dogs?
Isoflurane is more effective than esmolol and sodium nitroprusside in blunting multiple peripheral sympathetic responses to hypotension in a canine model.
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May not alter human anesthetic selection; leaves open translation of canine sympathetic blunting to clinical trials.
Jordan et al. (1993) studied this question.
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