Key result
Bariatric surgery is linked to an ~2% improvement in LVEF at 3 months.
Why the study?
Does bariatric surgery improve myocardial function in obese patients?
Observational (n=21)
Does bariatric surgery improve myocardial function in obese patients?
Absolute Event Rate: 64.8% vs 62.5%
p-value: p=0.003
Bariatric surgery significantly improves early myocardial function parameters in obese patients without prior cardiac disease.
Should not change practice; hypothesis-generating for myocardial effects of bariatric surgery in obesity.
The present pilot study included obese 21 patients (13 females and 8 males; mean age: 33.2 ± 11.0 years) who underwent bariatric surgery between December 2021 and June 2022. Echocardiographic evaluations and brain natriuretic peptide measurements were performed preoperatively and 3 months postoperatively. All patients underwent sleeve gastrectomy, and myocardial function was assessed using standard 2-dimensional M-mode Doppler echocardiography. The mean body mass index decreased from 44.8 ± 3.2 to 34.2 ± 2.9 kg/m 2 ( P < .001). Left ventricular (LV) ejection fraction increased from 62.5% ± 5.0% preoperatively to 64.8% ± 3.5% postoperatively ( P = .003). Interventricular septum, posterior wall thickness, systolic pulmonary artery pressure, P max, and isovolumic relaxation time decreased significantly ( P < .05). Left ventricular septal E′ and left ventricular lateral E ′ values increased ( P = .020 and .002, respectively). Although the mean pro- brain natriuretic peptide level decreased post-operatively, an increase was observed in 10 patients. Bariatric surgery significantly improves myocardial function, even in the absence of preoperative cardiac disease. However, given the short follow-up period, these findings reflect early myocardial changes. Further follow up with larger cohorts are warranted to interpret long-term clinical outcomes.
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Okmen et al. (2026) conducted an observational in Obesity (n=21). Bariatric surgery (sleeve gastrectomy) vs. Preoperative baseline was evaluated on Left ventricular ejection fraction (p=0.003).
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