Key result
Off-pump cardiac surgery prevented the significant decrease in right ventricular ejection fraction observed with on-pump surgery (32.4 to 31.9 vs 32.9 to 26.1 at 6 hours) in right coronary stenosis.
Why the study?
Does off-pump coronary surgery improve right ventricular function compared to on-pump surgery in patients undergoing multivessel coronary surgery with proximal severe right coronary lesions?
Cohort (n=29)
Does off-pump coronary surgery improve right ventricular function compared to on-pump surgery in patients undergoing multivessel coronary surgery with proximal severe right coronary lesions?
Off-pump coronary surgery appears to provide better right ventricular protection and preserves right ventricular ejection fraction compared to on-pump surgery in patients with severe right coronary stenosis.
May support off-pump preference for right ventricular protection in severe right coronary stenosis; leaves open randomized confirmation.
BACKGROUND AND OBJECTIVE: Myocardial protection during aortic clamp period may sometimes be inadequate, especially for the right. The aim of this study was to compare right ventricle function after cardiac surgery with or without bypass. METHODS: Patients undergoing multivessel coronary surgery with proximal severe right coronary lesion were included in a prospective observational cohort study including 29 patients undergoing coronary surgery with or without bypass. All patients were monitored with a pulmonary artery catheter with continuous right ventricular function. Right ventricular ejection fraction was measured at the arrival in ICU, 1, 3, 6, and 18 hours later. RESULTS: The number of grafts that was higher in the bypass group (4.0 +/- 1.3) than in the off-pump group (2.6 +/- 0.6, p = 0.001). In the on-pump group, the right ventricular ejection fraction significantly decreased from 32.9 +/- 2.8 at arrival in ICU to 26.1 +/- 2.4, 6 hours later whereas in the off-pump group, it did not significantly change (32.4 +/- 1.8 to 31.9 +/- 2.3). Meanwhile, at the same time intervals, CVP was significantly lower in the off-pump group. CONCLUSIONS: In patients with severe right coronary stenosis, off-pump cardiac surgery seemed to provide better right ventricular protection.
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Durand et al. (2006) conducted a cohort in Multivessel coronary surgery with proximal severe right coronary lesion (n=29). Off-pump coronary surgery vs. On-pump coronary surgery was evaluated on Right ventricular ejection fraction change at 6 hours. Off-pump cardiac surgery prevented the significant decrease in right ventricular ejection fraction observed with on-pump surgery (32.4 to 31.9 vs 32.9 to 26.1 at 6 hours) in right coronary stenosis.
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