Key result
CaNVAS ultrasound device continuously and non-invasively measures vascular parameters with 95% accuracy.
Why the study?
Vascular parameters indicate cardiovascular disorders and require continuous, non-invasive monitoring during surgeries and follow-up, but current gold-standard techniques rely on cuff-based or invasive catheters.
Does the CaNVAS ultrasound device accurately measure vascular parameters continuously and non-invasively compared to standard methods?
Observational (n=250)
Does the CaNVAS ultrasound device accurately measure vascular parameters continuously and non-invasively compared to standard methods?
Effect estimate: 12.5% CV
The CaNVAS ultrasound-based device demonstrates high accuracy (95%) for continuous, non-invasive measurement of vascular parameters like blood pressure and pulse wave velocity.
May support continuous non-invasive vascular monitoring; leaves open prospective validation against gold standards before clinical use.
In this paper, the feasibility of automated and accurate in vivo measurements of vascular parameters continuously and non-invasively using ultrasound sensor is presented. Vascular parameters such as pulse wave velocity (PWV), blood pressure (BP), arterial compliance (AC) and stiffness index (SI) are affluent indicators of cardiovascular disorders and needs to be monitored non-invasively and continuously during surgeries and follow-up procedures. Cuff based or invasive catheter techniques are considered as gold standard to measure BP and are fed manually to compute AC and SI which employ imaging algorithms. In this context, a Continuous and Non-Invasive Vascular Stiffness and Arterial Compliance Screener (CaNVAS) is developed to measure said parameters continuously and non-invasively using ultrasound sensor. Acoustic waves of 5 MHz (2.2 – 10 MHz) are driven through target arterial walls, reflected echoes captured, pre-processed and frequency shift is used to calculate PWV. It is observed that PWV measured using CaNVAS varies exponentially with BP values obtained from sphygmomanometer (BPMR-120) and this relationship is used to compute instantaneous values of BP. The proposed device is validated by performing measurements on 250 subjects in pre and post exercise conditions and found to have 95% accuracy and an average of 12.5% coefficient of variation.
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Sikkandar et al. (2023) conducted an observational in Cardiovascular monitoring (n=250). Continuous and Non-Invasive Vascular Stiffness and Arterial Compliance Screener (CaNVAS) vs. Sphygmomanometer (BPMR-120) was evaluated on Measurement accuracy and coefficient of variation (12.5% CV). The CaNVAS ultrasound device measured vascular parameters continuously and non-invasively with 95% accuracy and an average 12.5% coefficient of variation.
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