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Prospective study reveals equivalent survival outcomes between sentinel node biopsy and selective neck dissection in early oral cavity carcinoma, indicating biopsy is reliable for node-negative...
• Locorregional recurrence did not differed between both groups. • Overall survival between sentinel node biopsy and selective neck dissection group where not different. • Disease free survival between sentinel node biopsy and selective neck dissection group where not different. To describe the oncological results of a prospective study in the use of sentinel lymph node biopsy as part of the surgical treatment of squamous cell carcinoma T1/T2N0 of the oral cavity in comparison to the results of patients submitted to levels I, II and III SND. It was a prospective study in which seventy patients were divided into two groups, 35 being submitted to SND and the other 35 to SLB. In the SND group, locoregional recurrence occurred in 17.1%, with a 2.9% development of distant metastasis and 8.8% evolved with a second primary tumor. In the SLB, locoregional recurrence was observed in 7 patients (20.0%), 5.7% developed distant metastasis, and 5.7% had a second primary tumor. There was no significant difference between the two groups for both overall ( p = 0.521) and disease-free survival ( p = 0.753). A SLB is reliable for the management of clinically negative neck in patients with oral T1/T2N0 squamous cell carcinoma. Level III.
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Seferin et al. (2025) studied this question.
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