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August 7, 2026Head & NeckOpen Access

Sentinel Lymph Node Biopsy in Clinically N0 Gingivo‐Buccal Squamous Cell Carcinoma: A Prospective Feasibility Study

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Authors

VHVijay V. HaribhaktiSir H.N. Reliance Foundation Hospital and Research CentreTDT. DheerajJDA Software (United States)SSSaalim Y. SheikhSir H.N. Reliance Foundation Hospital and Research Centre

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Implication

Prospective trial evaluates sentinel lymph node biopsy safety in GBSCC N0 necks, suggesting reduced morbidity.

Key Points

  • Evaluate the feasibility and oncologic safety of sentinel lymph node biopsy in N0 necks with primary gingivo-buccal squamous cell carcinoma.
  • Prospective study of consecutive patients with clinically T1-T3 N0 gingivo-buccal squamous cell carcinoma undergoing primary surgery.
  • Sentinel lymph node biopsy performed using preoperative radiocolloid injection and SPECT imaging, followed by intraoperative localization with a gamma probe.
  • A supraomohyoid neck dissection was performed in all cases.
  • Sentinel nodes were identified in 39 patients, with 100% sensitivity and specificity.
  • Out of 746 nodes dissected, 14 were positive, with 12 being sentinel nodes detected in 8 patients.
  • At median follow-up of 27 months, 36 of 39 patients were NED (no evidence of disease).

Cite This Study

Haribhakti et al. (2026) studied this question.

synapsesocial.com/papers/6a758bae847ab6d26c01f24ehttps://doi.org/10.1002/hed.70403
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