Key result
Pre-discharge BNP levels >696 pg/ml strongly predicted 30-day re-admission or death in patients with decompensated heart failure compared to lower levels (RH 15.0; 95% CI 4.2-53.8; p<0.0001).
Why the study?
Do pre-discharge BNP levels predict early re-admission or death in patients admitted to a general medical unit for decompensated heart failure?
Population
100 consecutive patients admitted to a general medical unit due to decompensated HF, with 86 having >=1…
Comparison
Pre-discharge BNP levels >75th percentile vs Pre-discharge BNP levels <=75th percentile
Design
Cohort
Follow-up
30 days
Authors
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May support discharge risk stratification in general medical HF patients; hypothesis-generating, needs randomized confirmation.
Cohort (n=100)
No
Do pre-discharge BNP levels predict early re-admission or death in patients admitted to a general medical unit for decompensated heart failure?
Effect estimate: RH 15.0 (95% CI 4.2-53.8)
Absolute Event Rate: 56% vs 4%
p-value: p=<0.0001
Pre-discharge BNP levels strongly predict 30-day re-admission or death in elderly, comorbid patients admitted to general medical wards for decompensated heart failure.
Verdiani et al. (2005) conducted a cohort in Decompensated heart failure (n=100). Pre-discharge BNP >696 pg/ml (>75th percentile) vs. Pre-discharge BNP ≤696 pg/ml was evaluated on Early re-admission or death within 30 days (RH 15.0, 95% CI 4.2-53.8, p=<0.0001). Pre-discharge BNP levels >696 pg/ml strongly predicted 30-day re-admission or death in patients with decompensated heart failure compared to lower levels (RH 15.0; 95% CI 4.2-53.8; p<0.0001).
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