Key result
Tissue Doppler and strain rate imaging significantly correlated with ejection fraction and end-systolic dimension in patients with severe rheumatic mitral regurgitation (r=0.45, P<0.05).
Why the study?
Does tissue Doppler and strain rate imaging detect early left ventricular systolic dysfunction in patients with asymptomatic chronic severe rheumatic mitral regurgitation?
Population
100 subjects, including 25 normal subjects and 75 patients with asymptomatic chronic severe rheumatic mitral…
Comparison
Tissue Doppler and strain rate (SR) imaging vs Comparison across groups with varying severity…
Design
Cross-sectional
Authors
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May aid subclinical LV dysfunction detection in asymptomatic rheumatic MR; hypothesis-generating and requires prospective validation.
Observational (n=100)
Does tissue Doppler and strain rate imaging detect early left ventricular systolic dysfunction in patients with asymptomatic chronic severe rheumatic mitral regurgitation?
Effect estimate: r = 0.45
p-value: p=<0.05
Tissue Doppler and strain rate imaging correlate significantly with ejection fraction and end-systolic dimension, suggesting utility in the early detection of subclinical left ventricular dysfunction in asymptomatic severe rheumatic mitral regurgitation.
Gunjan et al. (2012) conducted an observational in Asymptomatic chronic severe rheumatic mitral regurgitation (n=100). Tissue Doppler and strain rate imaging vs. Normal subjects and standard echocardiographic parameters (EF and ESD) was evaluated on Correlation of tissue Doppler systolic indices and strain rate imaging with ejection fraction and end-systolic dimension (r = 0.45, p=<0.05). Tissue Doppler and strain rate imaging significantly correlated with ejection fraction and end-systolic dimension in patients with severe rheumatic mitral regurgitation (r=0.45, P<0.05).
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