Key result
Strain rate imaging demonstrated significantly decreased radial and longitudinal peak systolic strain rate in patients with severe mitral regurgitation compared to other groups (P=0.0003 to 0.0006).
Why the study?
Does strain rate imaging detect subclinical deterioration in left ventricular systolic function in asymptomatic patients with isolated mitral regurgitation?
Population
77 individuals: 54 asymptomatic patients with isolated non-ischaemic mitral regurgitation and 23 healthy…
Comparison
Standard echocardiographic examination and… vs Healthy subjects and patients with milder forms…
Design
Cross-sectional
Authors
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Strain rate imaging may identify subclinical LV impairment in asymptomatic severe MR; hypothesis-generating and requires prospective validation.
Observational (n=77)
Does strain rate imaging detect subclinical deterioration in left ventricular systolic function in asymptomatic patients with isolated mitral regurgitation?
p-value: p=0.0006, 0.0004, 0.0003
Strain rate imaging indices, corrected for geometry, may be useful in detecting subclinical deterioration in left ventricular systolic function in asymptomatic patients with severe mitral regurgitation.
Marciniak et al. (2007) conducted an observational in Isolated non-ischaemic mitral regurgitation (n=77). Strain rate imaging vs. Healthy subjects and patients with mild or moderate MR was evaluated on Radial and longitudinal peak systolic strain rate (p=0.0006, 0.0004, 0.0003). Strain rate imaging demonstrated significantly decreased radial and longitudinal peak systolic strain rate in patients with severe mitral regurgitation compared to other groups (P=0.0003 to 0.0006).
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