Why the study?
Are there regional left ventricular wall motion abnormalities in patients with chronic volume overload compared to normal subjects?
Population
19 subjects: 12 patients with chronic volume overload and 7 normal subjects.
Comparison
Computer-assisted analysis of left ventricular… vs Normal subjects (n=7).
Design
Case-control
Authors
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Regional wall motion abnormalities may occur in chronic volume overload; hypothesis-generating and should not yet change practice.
Are there regional left ventricular wall motion abnormalities in patients with chronic volume overload compared to normal subjects?
Chronic volume overload in valvular heart disease is associated with regional left ventricular wall motion abnormalities, specifically reduced inferoapical and anterior wall motion, which correlates with LV dynamic geometry alterations.
Donato et al. (1983) studied this question.
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