Key result
Repeat cardiac MRI at 12 months in healthy adults showed no significant changes in left ventricular ejection fraction (mean difference 0.9%, p=0.18), volumes, or mass compared to baseline.
Population
42 healthy adults with a 10-year cardiovascular risk <7.5%, normal exercise stress echocardiogram, and…
Design
Cohort, Single blinded observer for offline analysis
Follow-up
12 months
Authors
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Minimal CMR variability over 12 months in healthy adults aids serial scan interpretation; leaves open validation in cardiovascular disease cohorts.
Observational (n=42)
Single-blind
No
Effect estimate: Mean difference 0.9%
Absolute Event Rate: 71.2% vs 70.3%
p-value: p=0.18
The variability in CMR-derived LV measures at 12 months in healthy adults is minimal, allowing clinicians to confidently attribute small changes exceeding the smallest detectable change to disease-related factors.
Moody et al. (2015) conducted an observational in Healthy adults (n=42). Cardiac MRI at 12 months vs. Baseline Cardiac MRI was evaluated on Left ventricular ejection fraction (LVEF) (Mean difference 0.9%, p=0.18). Repeat cardiac MRI at 12 months in healthy adults showed no significant changes in left ventricular ejection fraction (mean difference 0.9%, p=0.18), volumes, or mass compared to baseline.
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