Key result
An automatic ECG detection algorithm successfully differentiated left ventricular hypertrophy patients from healthy volunteers using S-wave amplitude and ST-segment parameters (p=0.01 and p=0.04, respectively).
Why the study?
Can an automatic detection algorithm using a single lead ECG differentiate between patients with left ventricular hypertrophy and healthy volunteers?
Cross-Sectional (n=43)
Can an automatic detection algorithm using a single lead ECG differentiate between patients with left ventricular hypertrophy and healthy volunteers?
p-value: p=0.01 and 0.04
An automatic detection algorithm using single-lead ECG can significantly differentiate between patients with left ventricular hypertrophy and healthy volunteers, highlighting its potential application for wearable heart monitors.
Supports single-lead ECG LVH detection feasibility; hypothesis-generating, requires prospective validation before practice change.
In this work, an automatic detection algorithm for hypertrophic cardiomyopathy (HCM) is presented. Of particular interest is the algorithm’s ability to differentiate HCM subjects and healthy volunteers from a single lead ECG dataset. Suspected HCM subjects are identified by the primary clinical abnormality associated with HCM, left ventricular hypertrophy (LVH). In total, n =43 human subjects ECG datasets are investigated: n =21 healthy volunteers and n =22 left ventricular hypertrophy (LVH) patients. Significant differences of p -value 0.01 and 0.04 were found for the respective ECG parameters, S-wave amplitude and ST-segment, when differentiating between the LVH patients and healthy human volunteers.
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Denis et al. (2021) conducted a cross-sectional in Hypertrophic Cardiomyopathy / Left Ventricular Hypertrophy (n=43). Automatic ECG feature detection algorithm vs. Healthy volunteers was evaluated on Differentiation of LVH patients from healthy volunteers using S-wave amplitude and ST-segment (p=0.01 and 0.04). An automatic ECG detection algorithm successfully differentiated left ventricular hypertrophy patients from healthy volunteers using S-wave amplitude and ST-segment parameters (p=0.01 and p=0.04, respectively).
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