Key result
The combination of asymptomatic carotid stenosis and high LDL cholesterol significantly increased the risk of TIA, ischemic stroke, and myocardial infarction (OR 11.11; 95% CI 1.58-78.29).
Population
500 volunteers aged 50-79 years without clinical signs and symptoms of cerebrovascular disease from a…
Design
Cohort
Follow-up
2 years
Authors
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Identifies high-risk asymptomatic subgroup for closer surveillance; hypothesis-generating and should not yet change practice.
Cohort (n=500)
Effect estimate: OR 11.11 (95% CI 1.58-78.29)
Specific combinations of modifiable vascular risk factors, such as asymptomatic carotid stenosis with high LDL cholesterol, significantly increase the risk of ischemic events in an asymptomatic urban population.
Hadjiev et al. (2003) conducted a cohort in Ischemic stroke risk (n=500). Modifiable vascular risk factors was evaluated on Transient ischemic attacks (TIAs), ischemic stroke and myocardial infarction (OR 11.11, 95% CI 1.58-78.29). The combination of asymptomatic carotid stenosis and high LDL cholesterol significantly increased the risk of TIA, ischemic stroke, and myocardial infarction (OR 11.11; 95% CI 1.58-78.29).
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