Key result
Research on the kallikrein-kinin system has clarified its key role in cell morphogenesis, vascular permeability, inflammation, and blood pressure regulation.
Design
Review
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Extends foundational knowledge of vascular regulation; leaves open targeted therapies for hypertension and inflammation.
This review summarizes 90 years of research on the kallikrein-kinin system, highlighting its critical role in regulating blood pressure, vascular permeability, and inflammation.
Yarovaya et al. (2015) conducted a review in Kallikrein-kinin system physiology and pathology. Research on the kallikrein-kinin system has clarified its key role in cell morphogenesis, vascular permeability, inflammation, and blood pressure regulation.