Population
376 Caucasian normotensive twin pairs (182 monozygotic and 194 dizygotic) aged 25-79 years
Design
Cohort
Key result
Left ventricular mass has a sizeable genetic basis, with a heritability estimate of 0.59 (95% CI 0.5-0.67) among normotensive twins.
Authors
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Substantial LV mass heritability in normotensives supports genetic studies; leaves open clinical translation to hypertension risk or outcomes.
Cohort (n=752)
Effect estimate: Heritability 0.59 (95% CI 0.5-0.67)
Absolute Event Rate: 140.9% vs 140.2%
Left ventricular mass has a sizeable genetic basis with a heritability estimate of 0.59, independent of shared environmental effects.
Sharma et al. (2006) conducted a cohort in Normotensive (n=752). Monozygotic twins vs. Dizygotic twins was evaluated on Heritability of left ventricular mass (LVM) (Heritability 0.59, 95% CI 0.5-0.67). Left ventricular mass has a sizeable genetic basis, with a heritability estimate of 0.59 (95% CI 0.5-0.67) among normotensive twins.
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