Key result
This review highlights the early research establishing nitric oxide as a key signaling molecule in cardiovascular function and discusses drugs that interfere with the NO signaling cascade.
Design
Review
Authors
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Does not change current practice; leaves open further investigation of NO pathway modulators in cardiovascular disease.
This review summarizes the foundational research on nitric oxide as a key signaling molecule in the vascular system and its implications for cardiovascular therapeutics.
Ignarro et al. (1999) conducted a review in Cardiovascular disorders. Nitric oxide and drugs interfering with NO signaling cascade was evaluated. This review highlights the early research establishing nitric oxide as a key signaling molecule in cardiovascular function and discusses drugs that interfere with the NO signaling cascade.
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