What question did this study set out to answer?

To review the biological actions of nitric oxide as an inter- and intracellular signaling messenger with specific focus on human vascular biology and disease.

June 1, 1994Journal of Hypertension

Nitric oxide in the clinical arena

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Design

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Authors

ABAdam J. de BelderUniversity Hospitals Sussex NHS Foundation Trust MRMarek W. RadomskiVascular Medicine

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Implication

Nitric oxide mechanisms in vascular disease merit targeted study; leaves open whether modulation improves clinical outcomes.

Key Points

To review the biological actions of nitric oxide as an inter- and intracellular signaling messenger with specific focus on human vascular biology and disease.
Narrative synthesis of cellular and molecular evidence examining nitric oxide pathways in mammalian biology.
Evaluation of clinical implications and mechanisms linking nitric oxide signaling to human vascular disorders.
Nitric oxide acts as a ubiquitous signaling molecule that regulates fundamental processes including vascular tone, platelet activation, and neurotransmission.
The molecule exerts significant immunoregulatory, cytostatic, and cytotoxic effects that directly influence human vascular pathophysiology.

Cite This Study

Belder et al. (1994) studied this question.

synapsesocial.com/papers/6a926f56915bce628c4f2ce9 https://doi.org/10.1097/00004872-199406000-00001

Topics

Hypertension management

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Nitric oxide in the clinical arena

Discussion

Member takes

Implication

Key Points

Cite This Study

Topics

Nitric oxide in the clinical arena

Discussion

Member takes

Implication

Key Points

Cite This Study

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