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February 14, 2009PLoS ONEOpen Access

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

Hiroko Tsuruta Christopher J. Paddon Diana G. Eng Jacob R. Lenihan Tizita Horning Larry C. Anthony Rika Regentin Jay D. Keasling Neil S. Renninger Jack D. Newman

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Tsuruta et al. (2009) studied this question.

synapsesocial.com/papers/6a11e6ce45487b7639a58c26 https://doi.org/10.1371/journal.pone.0004489

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Qinghaosu (Artemisinin): The Price of SuccessOriginal Research · 2008 · 954 citations
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3High‐level production of amorpha‐4,11‐diene in a two‐phase partitioning bioreactor of metabolically engineered <i>Escherichia coli</i>Original Research · 2006 · 256 citations
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