Why the study?
Does echocardiographic evaluation of incremental left ventricular posterior wall thickening and thinning detect early cardiomyopathy in boys with Duchenne's muscular dystrophy compared to normal controls?
Population
24 boys with Duchenne's muscular dystrophy (DMD) and 32 normal controls
Comparison
Echocardiographic evaluation of incremental left… vs Normal controls
Design
Cohort
Follow-up
1 year
Authors
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May flag early DMD cardiomyopathy via delayed thinning; hypothesis-generating, needs prospective validation before clinical use.
Does echocardiographic evaluation of incremental left ventricular posterior wall thickening and thinning detect early cardiomyopathy in boys with Duchenne's muscular dystrophy compared to normal controls?
A novel echocardiographic technique evaluating incremental left ventricular wall thickness demonstrates that delayed diastolic relaxation (thinning) is an early sign of cardiomyopathy in boys with Duchenne's muscular dystrophy.
Goldberg et al. (1980) studied this question.
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