Key result
Children with Duchenne muscular dystrophy had significantly lower ejection fraction (P<0.001) and impaired diastolic function compared to healthy controls.
Population
124 children, comprising 62 patients with Duchenne Muscular Dystrophy and 62 healthy controls. The DMD group…
Design
Case-control
Authors
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Supports early echocardiography in pediatric DMD; leaves open whether screening improves outcomes in this population.
Observational (n=124)
p-value: p=<0.001
Echocardiographic analysis reveals that diastolic deterioration and subclinical systolic impairment begin in the early stages of Duchenne Muscular Dystrophy in children.
Bornaun et al. (2018) conducted an observational in Duchenne muscular dystrophy (n=124). Duchenne muscular dystrophy vs. Healthy children was evaluated on Echocardiographic parameters of left ventricular structure and function (p=<0.001). Children with Duchenne muscular dystrophy had significantly lower ejection fraction (P<0.001) and impaired diastolic function compared to healthy controls.
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