Key result
Increasing age in adult Nigerians without heart disease was correlated with a decrease in the QRS frontal axis and frontal QRS-T angle.
Why the study?
The prognostic cardiac axes and QRS-T angle are known to be affected by age, but the effect of age on these parameters has not been well studied in adult Nigerians.
Observational (n=85)
No
In adult Nigerians without clinical evidence of heart disease, increasing age is significantly associated with a superior shift in the QRS frontal axis and a decrease in the frontal QRS-T angle.
Answers are grounded in this paper and cite their sources.
Age-related QRS axis shifts should not alter ECG norms in Nigerians yet; leaves open longitudinal validation of prognostic relevance.
Background: P wave axis, QRS axis, T wave axis and QRS-T angle have prognostic values on cardiovascular morbidity and mortality, yet the effect of age on these important electrocardiographic parameters has not been well studied in adult Nigerians, knowing that some electrocardiographic parameters are affected by age. Objectives: This study was aimed at determining the effect of age on P frontal axis, QRS frontal axis, T frontal axis and frontal QRS-T angle among adult Nigerians. Methods: This was a retrospective study in which P frontal axis, QRS frontal axis and T frontal axis of adult patients who attended a university teaching hospital were determined from 12-lead ECG. Frontal QRS-T angle was calculated as the absolute difference between the QRS frontal axis and T wave frontal axis. The electrical axes and QRS-T angle were correlated with age. Results: There were 85 cases aged between 20 and 66 years, which included 42 males and 43 females. P frontal axis correlated positively and non-significantly with age (r = -0.032, p = 0.773), QRS frontal axis correlated negatively and significantly with age (r = -0.295, p = 0.006), T frontal axis correlated negatively and non-significantly with age (r = -0.002, p = 0.984), while frontal QRS-T angle correlated negatively and significantly with age (r = -0.266, p = 0.014). Conclusion: There were significant age related changes in both QRS frontal axis and frontal QRS-T angle. No significant age related changes were found in P frontal axis and T frontal axis.
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Chime et al. (2020) conducted an observational in Healthy adults (no history of heart disease) (n=85). Age was evaluated on Correlation between age and QRS frontal axis (r = -0.295, p=0.006). Increasing age in adult Nigerians without heart disease was correlated with a decrease in the QRS frontal axis and frontal QRS-T angle.
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