Population
Experimental preparation of a lung completely isolated from the general circulation, but with an intact…
Comparison
Experimental production of pulmonary congestion… vs Initial conditions (baseline)
Design
Preclinical
Authors
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Links experimental pulmonary congestion to reflex bradycardia and tachypnea; supports consensus on lung nerve endings but leaves open human translation.
The rapid shallow breathing attending congestion and edema of the lungs is due to the stimulation of nerve endings in the lungs, independent of chemical effects on the respiratory center.
Churchill et al. (1929) studied this question.
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