Effect of pulmonary venous congestion on respiratory rate in dogs.
Why the study?
Does pulmonary venous congestion increase respiratory rate in dogs?
Population
Dogs anaesthetized with alpha-chloralose (both spontaneously breathing and artificially ventilated)
Comparison
Pulmonary venous congestion produced by partial… vs Baseline state and cooling of cervical vagi to…
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Hypothesis-generating in canine models; leaves open vagal contributions to dyspnea in human congestion.
Structured PICO
Does pulmonary venous congestion increase respiratory rate in dogs?
P
Population
Dogs anaesthetized with alpha-chloralose (both spontaneously breathing and artificially ventilated)
I
Intervention
Pulmonary venous congestion produced by partial obstruction of the mitral valve sufficient to raise left atrial pressure by 5 mmHg
C
Comparator
Baseline state and cooling of cervical vagi to 8-9 degrees C
O
Outcome
Respiratory rate (frequency of breathing) and phrenic nerve activitysurrogate
Pulmonary venous congestion reflexly increases respiratory rate in dogs via vagal afferent pathways and rapidly adapting receptors.
Cite This Study
Kappagoda et al. (1989) studied this question.