Population
Anesthetized dogs
Design
Preclinical
Authors
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Differentiates arterial versus venular pulmonary constriction in dogs; leaves open site-specific mechanisms in human pulmonary hypertension.
In anesthetized dogs, 5-hydroxytryptamine acts as a pulmonary venular constrictor, whereas hypoxia primarily affects pulmonary arterial pressure.
Domingo M. Aviado (1960) studied this question.
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