Population
Anaesthetized rats
Comparison
Hypoxia, bilateral vagotomy, lung… vs Normoxia (air breathing) and baseline states
Design
Preclinical
Authors
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Rat data on pulmonary receptors during hypoxia do not inform clinical management; leaves open translational studies on irritant receptor reflexes.
In rats, cardiovascular changes during augmented breaths in hypoxia are likely driven by pulmonary irritant receptors rather than pulmonary stretch receptors.
Marshall et al. (1988) studied this question.
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