Why the study?
Does muscle afferent activation stimulate ventilation and cardiovascular responses during concurrent hypercapnia in humans?
Does muscle afferent activation stimulate ventilation and cardiovascular responses during concurrent hypercapnia in humans?
In the absence of central command, muscle metaboreflex and/or mechanoreflex activation stimulates ventilation during concurrent hypercapnia.
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May augment ventilatory drive during hypercapnia via muscle afferents; leaves open relevance to clinical cardiorespiratory disease.
Bruce et al. (2011) studied this question.
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