Why the study?
Does the combined activation of the muscle metaboreflex and ventilatory chemoreflex increase ventilation in healthy subjects?
Does the combined activation of the muscle metaboreflex and ventilatory chemoreflex increase ventilation in healthy subjects?
The muscle metaboreflex stimulates ventilation when there is concurrent chemoreflex activation, providing physiological insight into breathlessness and effort intolerance in certain disease states.
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May explain exertional dyspnea with concurrent reflex activation; hypothesis-generating before clinical translation.
Lykidis et al. (2009) studied this question.
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