Key result
Exaggerated systolic blood pressure reactivity to stress (≥20 mm Hg) was associated with a 72% greater risk of incident stroke in middle-aged men (RH 1.72; 95% CI 1.17-2.54).
Why the study?
Does exaggerated stress-induced blood pressure reactivity increase the risk of incident stroke in middle-aged men?
Population
2,303 middle-aged men from a population-based, longitudinal study of risk factors for ischemic heart disease…
Comparison
Exaggerated systolic blood pressure reactivity… vs Less reactive men
Design
Cohort
Follow-up
11.2 (±1.6) years
Authors
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Supports considering stress BP reactivity for risk stratification in middle-aged men; leaves open whether modifying reactivity reduces stroke incidence.
Cohort (n=2,303)
Does exaggerated stress-induced blood pressure reactivity increase the risk of incident stroke in middle-aged men?
Effect estimate: RH 1.72 (95% CI 1.17 to 2.54)
Exaggerated systolic blood pressure reactivity to stress is associated with a significantly increased risk of incident stroke in middle-aged men, with low socioeconomic status conferring additional risk.
Everson‐Rose et al. (2001) conducted a cohort in Incident stroke (n=2,303). Exaggerated systolic blood pressure reactivity to stress (≥20 mm Hg) vs. Less reactive men (<20 mm Hg) was evaluated on Incident stroke (RH 1.72, 95% CI 1.17 to 2.54). Exaggerated systolic blood pressure reactivity to stress (≥20 mm Hg) was associated with a 72% greater risk of incident stroke in middle-aged men (RH 1.72; 95% CI 1.17-2.54).
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