Why the study?
Does adenosine production correlate with myocardial oxygen consumption and coronary blood flow during physiological stimuli in conscious dogs?
Does adenosine production correlate with myocardial oxygen consumption and coronary blood flow during physiological stimuli in conscious dogs?
Increases in adenosine production by normally oxygenated myocardium can serve as the physiological mechanism for matching oxygen supply to increased oxygen demand.
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Supports adenosine's role in coronary flow-metabolism coupling in dogs; leaves open translation to human physiology.
Bacchus et al. (1982) studied this question.
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