Key result
AF affects ~67% of hemodialysis patients with devices, with dialysis episodes linked to lower potassium.
Why the study?
The timing of atrial fibrillation occurrence and related factors in hemodialysis patients with cardiac implantable electrical devices were evaluated.
Does the timing of hemodialysis affect the occurrence and burden of atrial fibrillation in patients with cardiac implantable electrical devices?
Observational (n=24)
No
Does the timing of hemodialysis affect the occurrence and burden of atrial fibrillation in patients with cardiac implantable electrical devices?
Answers are grounded in this paper and cite their sources.
Hemodialysis patients with cardiac implantable devices have a significantly higher risk of atrial fibrillation during dialysis, which appears to be associated with lower pre-dialysis serum potassium levels.
心臓植込みデバイスを用いて，血液透析（HD）患者の心房細動（AF）発生時期や発生因子について検討を行った．当センターにて外来フォロー中の心臓植込みデバイス装着HD患者24例（男性16例，平均年齢：74±10歳）を対象に，平均9±1ヵ月間のdevice保存データからAFの有無と発生情報を取得した．24例中16例（66.7％）にAFが確認され，単位時間当たりのAF発生件数は「HD中」が有意に多く（p＜0.01），単位時間当たりのAF burdenは「HD開始24時間前～HD開始」と「HD中」が，その他の時間帯より有意に多かった（p＜0.05）．またAF発生（＋）群とAF発生（－）群の患者背景に有意差は認めなかったが，HD中のAF発生（＋）群ではHD開始前の血清カリウム値が有意に低値（4.4±0.2mEq/L vs 4.7±0.2mEq/L，p＝0.01）であった．HD時はAF発生リスクが高く，さらに血清カリウム値低値との関連が示唆された．
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Aoki et al. (2021) conducted an observational in Hemodialysis patients with cardiac implantable electrical devices (n=24). Hemodialysis (exposure) vs. Non-hemodialysis periods was evaluated on Atrial fibrillation occurrence and burden (p=<0.01). Atrial fibrillation occurred in 66.7% of hemodialysis patients with implantable devices, with significantly higher occurrence during hemodialysis (p<0.01) linked to lower pre-dialysis potassium.
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