Key result
PVI linked to improved heart-focused anxiety, depression, and quality of life at 6 months.
Why the study?
Atrial fibrillation is associated with anxiety, depression, and chronic stress, and vice versa, prompting an evaluation of the effects of pulmonary vein isolation on psychological factors.
Does pulmonary vein isolation improve heart-focused anxiety, general anxiety, depression, and quality of life in patients with atrial fibrillation?
Observational (n=118)
Does pulmonary vein isolation improve heart-focused anxiety, general anxiety, depression, and quality of life in patients with atrial fibrillation?
Pulmonary vein isolation significantly improves heart-focused anxiety, general anxiety, depression, and quality of life in patients with atrial fibrillation at 6 months.
May support PVI for anxiety and QoL gains in AF; hypothesis-generating, requiring RCTs before practice change.
(1) Background: Atrial fibrillation (AF) is associated with anxiety, depression, and chronic stress, and vice versa. The purpose of this study was to evaluate potential effects of pulmonary vein isolation (PVI) on psychological factors. (2) Methods: Psychological assessment was performed before PVI as well as after six months. (3) Results: A total of 118 patients [age 64 ± 9 years, 69% male, left ventricular ejection fraction 57 ± 8%, 56% paroxysmal AF] undergoing PVI were included. After PVI, significant improvements were observed in the mean total heart-focused anxiety (HFA) score, as well as in the Cardiac Anxiety Questionnaire (CAQ) sub-scores: HFA attention, HFA fear, and HFA avoidance scores. Subgroup analyses showed an association of improvement with freedom of documented AF recurrence. Mean scores of general anxiety and depression evaluated by the Hospital Anxiety and Depression Scale (HADS) decreased significantly after PVI in all subgroups regardless of AF recurrence. Further, both physical and mental composite scores of the Short Form Health Survey (SF-12) increased significantly from baseline. (4) Conclusions: PVI results in a significant reduction in HFA. Improvements in general anxiety and depressive symptoms did not seem to be related only to rhythm control per se. Therefore, CAQ may represent a more specific evaluation tool as HADS in patients with AF.
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Pavlicek et al. (2022) conducted an observational in Atrial fibrillation (n=118). Pulmonary vein isolation (PVI) vs. Baseline (before PVI) was evaluated on Psychological factors including heart-focused anxiety, general anxiety, and depression. Pulmonary vein isolation significantly improved heart-focused anxiety, general anxiety, depression, and quality of life at 6 months compared to baseline.
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