Why the study?
While peri-procedural efficacy of PVI for AF is well documented, early patient-reported outcomes and quality of life remain under-characterized.
Does pulmonary vein isolation improve early patient-reported outcomes and quality of life in patients with atrial fibrillation?
Does pulmonary vein isolation improve early patient-reported outcomes and quality of life in patients with atrial fibrillation?
Single center survey evaluates quality of life improvements after pulmonary vein isolation in patients with atrial fibrillation, suggesting enhanced recovery and satisfaction.
Background/Introduction Pulmonary vein isolation (PVI) is the cornerstone rhythm control therapy for atrial fibrillation (AF) management, offering better rhythm control and symptoms relief. While peri-procedural efficacy is well documented, early patient-reported outcomes (PROs) and quality of life remain under-characterized. Understanding patients’ subjective experiences may inform post-procedural care and expectation management. Purpose To evaluate self-reported health status, functional recovery, and overall satisfaction in the early period (30–60 days) following PVI in patients with AF. Methods A single center, cross-sectional survey was conducted in 100 consecutive patients (aged 30–70 years, both sexes) who underwent successful PVI procedure (at our university clinic) in early follow up period of 30-60 days. An 11-item questionnaire assessed: general health, physical activity, fatigue, dyspnea, palpitations, anxiety/stress, sleep quality, emotional stability, social life, return to work, and overall satisfaction. Data were summarized using frequencies and percentages. Where appropriate, associations were tested using Chi-square or Fisher’s exact test; p < 0.05 was considered statistically significant. Results Patient-reported outcomes are summarized in Table 1. Most patients reported improvement or stability in general health (89%; p < 0.001), with 46% "much improved." Physical activity improved in 56% (p = 0.002). Fatigue and dyspnea were rare or absent in 61% and 80%, respectively (p < 0.01). Palpitations were markedly reduced (70% rarely/never; p = 0.003). Anxiety/stress improved in 87% (p < 0.001) and sleep quality in 71% (p = 0.006). Emotional stability ("often" or "always positive") was observed in 78% (p < 0.001), and social activity improved in 71% (p = 0.004). Regarding recovery, 51% returned to daily activities within 2 weeks, and 79% within 3 months. Overall satisfaction was high, with 81% satisfied or very satisfied and 6% dissatisfied (p < 0.001). Conclusion(s) Early post PVI follow up period was associated with significant improvements in physical function, psychological well-being, and social participation, with high satisfaction rates and early return to daily activities. These findings support the early significant benefits of PVI on patient-perceived quality of life in routine clinical practice.
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Taleski et al. (2026) studied this question.
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