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January 1, 2022Vessel PlusOpen Access

Cardiac amyloidosis: the pathologist’s point of view

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Key result

Cardiac amyloidosis often requires tissue sampling to determine the specific protein type for targeted treatment.

Why the study?

Cardiac amyloidosis presentation is often elusive leading to diagnostic delay, requiring tissue sampling and pathological typing of deposited proteins to direct specific treatment.

Design

Review

Authors

MGMonica De GaspariGeneral CardiologyNFNicoletta FinatoHeart Failure / Cardiomyopathy
Cristina Basso
Cristina BassoPreventive Cardiology

Discussion

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Implication

Tissue sampling remains essential for subtyping; leaves open validation of non-invasive alternatives in cardiac amyloidosis.

Structured PICO

P
Population
Patients with cardiac amyloidosis

This review outlines the pathological features of cardiac amyloidosis, emphasizing the necessity of tissue sampling and protein typing to guide specific treatments.

Cite This Study

Gaspari et al. (2022) conducted a review in Cardiac amyloidosis. Cardiac amyloidosis is an infiltrative disease often requiring tissue sampling and pathological analysis to determine the specific protein type for targeted treatment.

synapsesocial.com/papers/6a122302c031bb6829a5f8afhttps://doi.org/10.20517/2574-1209.2022.05

Topics

Cardiac amyloidosisCardiomyopathyHeart failureHFrEF treatment
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Importance of Left Atrial Infiltration in Cardiac Transthyretin Amyloidosis2021 · 165 citations
  2. 2Pericardial Effusion and Multiple Organ Involvement Are Independent Predictors of Mortality in Patients with Systemic Light Chain Amyloidosis2015 · 15 citations
  3. 3Diagnostic accuracy of subcutaneous abdominal fat tissue aspiration for detecting systemic amyloidosis and its utility in clinical practice2006 · 224 citations
  4. 4Identification of prognostic markers in transthyretin and AL cardiac amyloidosis*2016 · 78 citations
  5. 5Medin-amyloid: A recently characterized age-associated arterial amyloid form affects mainly arteries in the upper part of the body2005 · 77 citations