Key result
Hypertension affects ~87% of Kazakh patients with AF alongside high rates of CAD and CHF.
Why the study?
Atrial fibrillation is the most common persistent heart rhythm disorder, but its clinical predictors in the Kazakh population required assessment.
What are the clinical predictors and associated comorbidities of atrial fibrillation in the Kazakh population?
Observational (n=75)
Yes
What are the clinical predictors and associated comorbidities of atrial fibrillation in the Kazakh population?
In the Kazakh population, atrial fibrillation is predominantly associated with traditional risk factors including hypertension, coronary artery disease, and high body mass index.
Answers are grounded in this paper and cite their sources.
Hypertension predominates among Kazakh AF comorbidities; leaves open causal predictors and generalizability pending longitudinal data.
BACKGROUND: Atrial fibrillation (AF) is the most common persistent heart rhythm disorder. AIM: Assessment of clinical predictors of atrial fibrillation in the Kazakh population. METHODS: An analytical clinical and epidemiological study of 75 patients with AF of Kazakh nationality. Descriptive analysis of medical records was carried out and the results of laboratory and instrumental research methods. Statistical analysis was carried out using the Statistica 6.0 Software package from StatSoft Inc. (USA) and MS Excel. RESULTS: In the majority of the studied patients (86.7%), atrial fibrillation was associated with hypertension, in 49.3% of patients was diagnosed with coronary artery disease. A permanent form of atrial fibrillation was observed in 63%, in 20% AF manifested itself in the form of paroxysms, in 17% AF was persistent. AF, which arose against the background of CHF, was established in 41.3% of the patients studied by us, while a decrease in LVEF below 40% was observed in 21.3% of the examined patients. In our study, diabetes mellitus was diagnosed as a comorbid pathology in 24% of patients and diabetes mellitus correlated with permanent AF in 66.7%. Thyroid pathology was observed in 9.3% cases. CRHD as a concomitant disease occurred in 12% of cases. In 5.7% of cases, AF was registered as idiopathic (primary) without a history of cardiovascular and concomitant pathology. Smoking as a risk factor was observed in 16%, alcohol consumption, was noted by 8 patients (10.7%). In 40% of cases, patients with AF were obese, 45.3% of the patients were overweight (BMI ≥25).
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Taizhanova et al. (2022) conducted an observational in Atrial fibrillation (n=75). In Kazakh patients with atrial fibrillation, the most prevalent clinical risk factors were arterial hypertension (86.7%), coronary artery disease (49.3%), and chronic heart failure (41.3%).
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