Key result
Antihypertensive drugs linked to a ~7 mmHg SBP reduction accurately predicted by machine learning.
Why the study?
Uncontrolled blood pressure causes major adverse outcomes, yet few studies have used machine learning to predict changes in blood pressure.
Can machine learning algorithms predict changes in systolic and diastolic blood pressure in hypertensive patients?
Observational (n=100)
Yes
Can machine learning algorithms predict changes in systolic and diastolic blood pressure in hypertensive patients?
Effect estimate: Mean difference 7.1 mmHg
Absolute Event Rate: 151.1% vs 158.2%
p-value: p=<0.001
Machine learning models can effectively predict whether hypertensive patients will experience a decrease in blood pressure following antihypertensive treatment based on various clinical and sociodemographic factors.
PURPOSE OF REVIEW: This retrospective study investigated factors that influence the occurrence of decreased systolic and diastolic blood pressure including sociodemographic and economic factors, hypertension duration, cigarette consumption, alcohol consumption, duration of smoking, type of cigarettes, exercise, salt consumption, sleeping pills consumption, insomnia, and diabetes. These factors were applied to predict the reality of systolic and diastolic decrease using the machine learning algorithm Naïve Bayes, artificial neural network, logistic regression, and decision tree. RECENT FINDINGS: The increase in blood pressure, both systolic and diastolic, is very harmful to the health because uncontrolled high systolic and diastolic blood pressure can cause various diseases such as congestive heart failure, kidney failure, and cardiovascular disease. There have been many studies examining the factors that influence the occurrence of hypertension, but few studies have used machine learning to predict hypertension. The machine learning models performed well and can be used for predicting whether a person with hypertension with certain characteristics will experience a decrease in their systolic or diastolic blood pressure after treatment with antihypertensive drugs.
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Nuryunarsih et al. (2023) conducted an observational in Hypertension (n=100). Antihypertensive drugs vs. Baseline (before medication) was evaluated on Change in systolic blood pressure (Mean difference 7.1 mmHg, p=<0.001). Antihypertensive drugs significantly reduced mean systolic blood pressure by 7.1 mmHg and diastolic blood pressure by 3.3 mmHg, with machine learning models predicting these decreases with up to 95% accuracy.
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