Key result
Advances in radiotherapy techniques have allowed for increased sparing of the heart and its substructures, resulting in decreased rates of long-term cardiotoxicity for cancer patients.
Why the study?
As cancer survival outcomes improve, there is growing concern regarding survivorship and the long-term effects of radiotherapy on cardiac function.
What are the cardiovascular toxicities of radiation therapy and how can radiation to the heart be minimized?
What are the cardiovascular toxicities of radiation therapy and how can radiation to the heart be minimized?
This review provides an overview of radiation-induced heart disease, emphasizing the need to understand cardiac injury parameters and utilize techniques that minimize cardiac radiation exposure in cancer survivors.
Encourages heart-sparing radiotherapy planning in cancer patients; leaves open prospective validation of long-term outcomes.
As cancer survival outcomes improve, there is a growing focus on survivorship and long-term morbidity after cancer treatment. In particular, there has been concern about the long-term effects of radiotherapy on cardiac function. In this review, we discuss the cardiac effects of radiotherapy in the context of potential confounding factors, examine the potential parameters of interest when studying and modeling cardiac injury, highlight current treatment techniques to minimize radiation to the heart, and consider future areas of improvement and study.
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Lewis et al. (2019) conducted a review in Cancer (Breast, Hodgkin Lymphoma, Lung) and Radiation-Induced Heart Disease. Radiotherapy was evaluated. Advances in radiotherapy techniques have allowed for increased sparing of the heart and its substructures, resulting in decreased rates of long-term cardiotoxicity for cancer patients.
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