Key result
A fetal pulmonary venous Doppler forward/reverse VTI ratio <5 strongly predicted the need for emergent atrial septoplasty in newborns with HLHS (sensitivity 0.88, specificity 0.97).
Why the study?
Does fetal pulmonary venous Doppler flow pattern predict the need for emergent atrial septoplasty in newborns with hypoplastic left heart syndrome?
Observational (n=41)
Does fetal pulmonary venous Doppler flow pattern predict the need for emergent atrial septoplasty in newborns with hypoplastic left heart syndrome?
Effect estimate: Sensitivity 0.88, Specificity 0.97 (95% CI 0.49-0.99 (sensitivity), 0.82-0.99 (specificity))
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In fetuses with hypoplastic left heart syndrome, a pulmonary venous Doppler forward/reverse VTI ratio of <5 strongly predicts the need for emergent atrial septoplasty in the newborn period.
Michelfelder et al. (2005) conducted an observational in Hypoplastic left heart syndrome (HLHS) (n=41). Fetal pulmonary venous Doppler (PVD) flow analysis was evaluated on Neonatal emergent atrial septoplasty (EAS) (Sensitivity 0.88, Specificity 0.97, 95% CI 0.49-0.99 (sensitivity), 0.82-0.99 (specificity)). A fetal pulmonary venous Doppler forward/reverse VTI ratio <5 strongly predicted the need for emergent atrial septoplasty in newborns with HLHS (sensitivity 0.88, specificity 0.97).
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