Key result
Beta-carotene supplementation attenuated cardiac remodeling induced by one-month tobacco-smoke exposure in rats, preserving cardiac output (0.099 l/min) compared to ETS alone (0.087 l/min).
Why the study?
Does beta-carotene supplementation attenuate cardiac remodeling induced by tobacco-smoke exposure in rats?
RCT (n=44)
randomized
Does beta-carotene supplementation attenuate cardiac remodeling induced by tobacco-smoke exposure in rats?
Absolute Event Rate: 0.099% vs 0.087%
p-value: p=>0.05
Beta-carotene supplementation attenuates functional and morphological cardiac remodeling induced by one-month tobacco-smoke exposure in a rat model.
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Should not change clinical practice; extends preclinical evidence for beta-carotene in smoke-related remodeling.
Zornoff et al. (2005) conducted an RCT in Cardiac remodeling induced by tobacco smoke exposure (n=44). Beta-carotene supplementation vs. Air (control) and tobacco smoke exposure alone was evaluated on Cardiac output (l/min) (p=>0.05). Beta-carotene supplementation attenuated cardiac remodeling induced by one-month tobacco-smoke exposure in rats, preserving cardiac output (0.099 l/min) compared to ETS alone (0.087 l/min).
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