Key result
CCM bridges an advanced HF patient to recovery, avoiding the need for an LVAD.
Why the study?
Does Cardiac Contractility Modulation improve clinical outcomes and serve as a bridge to recovery in a patient with advanced HFrEF evaluated for LVAD?
Case Report (n=1)
No
Does Cardiac Contractility Modulation improve clinical outcomes and serve as a bridge to recovery in a patient with advanced HFrEF evaluated for LVAD?
Cardiac Contractility Modulation may serve as an effective bridge to recovery in patients with advanced HFrEF who are candidates for LVAD therapy.
Answers are grounded in this paper and cite their sources.
May support CCM as bridge to recovery in advanced HFrEF; leaves open confirmation in prospective trials.
This case report illustrates the effects of CCM as a bridge to recovery in a patient who has been a candidate for LVAD. After CCM the patient hase become stable in NYHA class II, with no further acute HF episodes and a significant clinical and functional improvements. Consequently, the patient was no longer an LVAD candidate, as CCM had acted as a bridge to recovery, making the advanced HF designation no longer applicable. The ease of implantation, uneventful procedural recovery, extraordinary device longevity, and favorable risk profile all position CCM as an important tool in the treatment of advanced HFrEF patients candidate to LVAD therapy, serving as a bridge to recovery.Further large-scale randomized controlled trials are needed to confirm the long-term benefits of CCM therapy in this particular population subgroup, helping a better patient selection.
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Menichetti et al. (2025) conducted a case report in Advanced heart failure with reduced ejection fraction (HFrEF) (n=1). Cardiac Contractility Modulation (CCM) was evaluated on Clinical and functional improvement. Cardiac Contractility Modulation improved clinical and functional status in a patient with advanced heart failure, serving as a bridge to recovery and avoiding the need for an LVAD.
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