Key result
Modern imaging techniques accurately delineate both the myocardial area at risk and final infarct size in vivo, offering practical value for assessing new treatments in clinical trials.
Modern imaging techniques allow for accurate in vivo delineation of myocardial area at risk and final infarct size, which is valuable for assessing new treatments in clinical trials.
May refine MI trial endpoints with imaging; leaves open prospective outcome validation.
Assessment of new treatments for patients with acute myocardial infarction requires a study of the area at risk of undergoing necrosis during coronary occlusion and estimation of the size of the necrotic area following the intervention. In contrast to the situation in the laboratory, direct staining of the area at risk and the necrotic zone is not possible in vivo. Modern imaging techniques opened new possibilities to delineate both the area at risk and the final infarct size with good accuracy in vivo. This article reviews the most commonly used techniques and examines the practical value in using them in clinical trials.
No takes yet. Share an insight, caveat, or question.
Udo Sechtem (2001) conducted a review in Acute myocardial infarction. Modern imaging techniques was evaluated. Modern imaging techniques accurately delineate both the myocardial area at risk and final infarct size in vivo, offering practical value for assessing new treatments in clinical trials.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: