While conventional clinical and laboratory methods are accurate for diagnosing myocardial infarction, advanced imaging modalities are optimal for accurately quantitating infarct size.
Supports conventional MI diagnosis; leaves open whether advanced imaging should guide routine infarct sizing.
In order to provide timely and proper therapy for patients with myocardial infarction, accurate diagnosis is essential. To assess the impact of therapy and to aid in long-term prognostication, it is also desirable to quantitate accurately the extent of infarct size. For diagnostic purposes, the conventional methods of clinical evaluation, 12-lead electrocardiography, and analysis of serum enzymes are accurate. However, more sophisticated approaches, such as radionuclide, echocardiographic, and magnetic resonance imaging, can be useful adjuncts for diagnosis. In contrast, the sizing of infarcts is often best performed using imaging methods. This paper reviews the application of various techniques to accomplish the goals of accurate diagnosis and quantitation of myocardial infarction.
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Blackwell et al. (1991) studied this question.
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