Why the study?
Does percutaneous left atrial appendage closure prevent stroke and bleeding in patients with non-valvular atrial fibrillation and restrictions to oral anticoagulation?
Population
91 patients with non-valvular atrial fibrillation, high stroke risk and restrictions to oral anticoagulation…
Comparison
Percutaneous Left Atrial Appendage Closure using… vs Expected rates based on CHA2DS2VASc and HASBLED…
Design
Cohort
Follow-up
128.6 patient-years
Key result
Left atrial appendage closure in patients with non-valvular atrial fibrillation achieved a 97.8% procedural success rate and a 2.2% stroke rate over 128.6 patient-years of follow-up.
Authors
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Supports LAA closure feasibility in anticoagulation-restricted NVAF; leaves open randomized confirmation of stroke prevention.
Observational (n=91)
Yes
Does percutaneous left atrial appendage closure prevent stroke and bleeding in patients with non-valvular atrial fibrillation and restrictions to oral anticoagulation?
In a real-world Brazilian registry, percutaneous left atrial appendage closure showed high procedural success and low rates of stroke and bleeding in NVAF patients with restrictions to oral anticoagulation.
Guérios et al. (2017) conducted an observational in Non-valvular atrial fibrillation (NVAF) (n=91). Left atrial appendage closure (LAAC) using Amplatzer cardiac plug or Watchman device was evaluated on Procedural success rate. Left atrial appendage closure in patients with non-valvular atrial fibrillation achieved a 97.8% procedural success rate and a 2.2% stroke rate over 128.6 patient-years of follow-up.