Why the study?
Does myocardial echo intensity differ between patients with pathological left ventricular hypertrophy and physiological hypertrophy or normal subjects?
Does myocardial echo intensity differ between patients with pathological left ventricular hypertrophy and physiological hypertrophy or normal subjects?
Quantifying myocardial echo intensity can differentiate pathological left ventricular hypertrophy from physiological hypertrophy in athletes, potentially reflecting increased myocardial collagen content.
May support echo intensity quantification to distinguish pathological from physiological LVH; hypothesis-generating and requires prospective validation.
Summary An approach by quantifying the echoes arising from hypertrophied myocardium, is described in patients with left ventricular hypertrophy of various causes, including hypertrophic cardiomyopathy. Amplitude of echoes judged by pixel count was significantly increased in patients with hypertrophic cardiomyopathy, hypertension and aortic stenosis as compared with normals and athletes with a comparable increase in left ventricular mass. It is suggested that the increase in echo intensity reflects an increase in myocardial collagen content.
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D G Gibson (1985) studied this question.
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